منابع مشابه
Exogenous growth factors stimulate the regeneration of ganglion cells in the chicken retina.
Recent reports have found that the posthatch chicken retina has the capacity for neuronal regeneration. The purpose of this study was to test whether the types of cells destroyed by neurotoxic lesions influence the types of cells that are regenerated, and whether exogenous growth factors stimulate neural regeneration in the chicken retina. N-methyl-D-aspartate (NMDA) was used to destroy amacrin...
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Neural progenitors at the retinal margin of the post-hatch chicken normally produce amacrine and bipolar cells, but not photoreceptor or ganglion cells. The purpose of this study was to test whether exogenous growth factors influence the types of cells produced by progenitors at the retinal margin. We injected insulin, FGF2 or a combination of insulin and FGF2 into the vitreous chamber of post-...
متن کاملRetinal ganglion cell neuroprotection by growth factors and exosomes: lessons from mesenchymal stem cells
Retinal ganglions cells (RGCs) are responsible for propagating electrochemical information from the eye to the brain along their axons which make up the optic nerve. The loss of RGCs is characteristic in several conditions such as glaucoma and traumatic optic neuropathy and leads to visual loss and blindness. While no therapy exists to directly treat RGCs, the use of bone marrow-derived mesench...
متن کاملBlood Cell Growth Factors
SUMMARY Growth factors or colony stimulating factors (CSFs)recently became the subject of headlines around the world. Many published articles in the last few years indicate that the CSFs can correct anemia and pancytopenia of the great majority of patients. Recombinant CSFs are available to the many scientific and therapeutic centers in the U.S.A, Europe and Japan these days. Erythrop oieti...
متن کاملGrowth and Growth Factors
SOCS2 inactivation, which leads to growth hormone hypersensitivity and overgrowth, is selected as the mechanism of the year in this chapter. The second paper shows that PPAR plays a role in the growth of male mice. Under new paradigms, we learn that the disruption of a paternally expressed gene from the Gnas locus, XL s, is associated with poor postnatal growth, and we also discover a new molec...
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ژورنال
عنوان ژورنال: Nature
سال: 1973
ISSN: 0028-0836,1476-4687
DOI: 10.1038/242209a0